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Nature Biotechnology volume 43, pages 143–146 (2025)
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Academic medical centers must play a crucial part in overcoming cell and gene therapy development hurdles by establishing institutional frameworks that offer comprehensive support extending beyond financial assistance.
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Saez-Ibañez, A. R. et al. Nat. Rev. Drug Discov. 21, 631–632 (2022).
Article PubMed Google Scholar
Kuzmin, D. A. et al. Nat. Rev. Drug Discov. 20, 173–174 (2021).
Article CAS PubMed Google Scholar
Vokinger, K. N., Avorn, J. & Kesselheim, A. S. N. Engl. J. Med. 388, 292–295 (2023).
Article PubMed Google Scholar
Seyhan, A. A. Transl. Med. Commun. 4, 1–19 (2019).
Article Google Scholar
NEWDIGS Consortium at Tufts Medical Center. Are cell and gene therapy programs a better bet? Tufts Medical Center https://newdigs.tuftsmedicalcenter.org/wp-content/uploads/2023/10/NEWDIGS-Success-Rate-Comparison-2023F210v056.pdf (Tufts Medicine, 9 October 2023).
Cohen, J. P. Science continues to outpace commericalization of cell and gene therapies. Forbes Newslett. https://www.forbes.com/sites/joshuacohen/2024/03/04/science-continues-to-outpace-commercialization-of-cell-and-gene-therapies/ (2024).
RePORT. Estimates of funding for various research, condition, and disease categories (RCDC). NIH https://report.nih.gov/funding/categorical-spending#/ (14 May 2024).
Kassir, Z., Sarpatwari, A., Kocak, B., Kuza, C. C. & Gellad, W. F. J. Am. Med. Assoc. 323, 890–891 (2020).
Article Google Scholar
Aiuti, A., Pasinelli, F. & Naldini, L. Nat. Med. 28, 1985–1988 (2022).
Article CAS PubMed Google Scholar
Fox, T. et al. Nat. Med. 29, 518–519 (2023).
Article CAS PubMed Google Scholar
Lee, N. K. & Chang, J. W. Ann. Lab. Med. 44, 314–323 (2024).
Article CAS PubMed PubMed Central Google Scholar
Scher, J. U. & Schett, G. Nat. Rev. Rheumatol. 17, 119–124 (2021).
Article PubMed Google Scholar
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Gene and Cell Therapy Institute, Mass General Brigham, Cambridge, MA, USA
Nandhitha Uma Naresh, Dana Hammill, Roger J. Hajjar & Nathan L. Yozwiak
New York, NY, USA
Mark Kessel
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Correspondence to Nathan L. Yozwiak.
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Uma Naresh, N., Hammill, D., Kessel, M. et al. As new cell and gene therapies emerge from academia, we must RISE to the opportunity. Nat Biotechnol 43, 143–146 (2025). https://doi.org/10.1038/s41587-024-02520-9
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DOI: https://doi.org/10.1038/s41587-024-02520-9
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